Berthold Hocher Selected Research

8- (3- amino- 1- piperidinyl)- 7- (2- butyn- 1- yl)- 1- ((4,6- dimethyl- 2- pyrimidinyl)methyl)- 3- methylxanthine

7/2013

The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats.

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Berthold Hocher Research Topics

Disease

22	Fibrosis (Cirrhosis) 02/2022 - 04/2002
18	Chronic Renal Insufficiency 01/2022 - 05/2005
17	Hypertension (High Blood Pressure) 06/2022 - 12/2002
14	Chronic Kidney Failure (Chronic Renal Failure) 01/2022 - 08/2002
12	Cardiovascular Diseases (Cardiovascular Disease) 06/2022 - 02/2003
12	Albuminuria 01/2019 - 04/2006
12	Birth Weight (Birth Weights) 01/2018 - 11/2006
11	Diabetic Nephropathies (Diabetic Nephropathy) 01/2020 - 04/2006
10	Heart Failure 11/2021 - 06/2006
10	Type 2 Diabetes Mellitus (MODY) 01/2019 - 01/2012
9	Inflammation (Inflammations) 09/2022 - 12/2005
7	Acute Kidney Injury (Acute Renal Failure) 09/2022 - 11/2003
7	Neoplasms (Cancer) 11/2021 - 01/2004
7	Pre-Eclampsia (Preeclampsia) 01/2018 - 05/2006
7	Pulmonary Hypertension 09/2015 - 09/2003
6	Disease Progression 11/2021 - 04/2002
6	Renovascular Hypertension (Goldblatt Syndrome) 11/2013 - 04/2002
6	Body Weight (Weight, Body) 01/2013 - 01/2012
6	Proteinuria 02/2010 - 08/2002
5	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 01/2022 - 05/2006
5	Insulin Resistance 01/2021 - 11/2006
5	Stroke (Strokes) 01/2019 - 04/2007
5	Myocardial Infarction 01/2019 - 04/2007
4	Ischemia 09/2022 - 11/2010
4	Infections 07/2022 - 12/2011
4	Premature Birth (Birth, Premature) 01/2022 - 09/2012
4	Pneumonia (Pneumonitis) 01/2022 - 08/2008
4	Vascular Calcification 09/2021 - 02/2011
4	Renal Insufficiency (Renal Failure) 02/2017 - 04/2006
4	Diabetes Mellitus 01/2017 - 09/2003
3	Vitamin D Deficiency 01/2021 - 01/2012
3	Cardiomegaly (Heart Hypertrophy) 01/2018 - 01/2003
3	Necrosis 06/2011 - 12/2005
3	Uremia 02/2011 - 05/2005
2	Rheumatoid Arthritis 07/2022 - 01/2022
2	Malnutrition (Nutritional Deficiencies) 06/2022 - 10/2014
2	COVID-19 01/2022 - 01/2021
2	Pulmonary Arterial Hypertension 01/2022 - 05/2004
2	IGA Glomerulonephritis (IGA Nephropathy) 01/2022 - 02/2021

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 07/2022 - 08/2002
14	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 11/2006
12	CreatinineIBA 01/2022 - 09/2003
12	Vitamin D FDA LinkGeneric 01/2021 - 05/2005
12	LinagliptinIBA 01/2019 - 01/2011
10	Endothelin-1 (Endothelin 1)IBA 01/2017 - 09/2003
10	Endothelins (Endothelin)IBA 11/2014 - 08/2002
9	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2022 - 01/2011
9	Biomarkers (Surrogate Marker)IBA 01/2019 - 11/2004
8	SaltsIBA 01/2022 - 08/2002
7	SodiumIBA 01/2019 - 08/2002
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2015 - 09/2003
6	ReninIBA 01/2012 - 01/2004
6	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2011 - 10/2006
5	Telmisartan (Micardis)FDA Link 02/2022 - 01/2012
5	AlbuminsIBA 01/2022 - 09/2003
5	Angiotensin Receptor AntagonistsIBA 01/2021 - 11/2010
5	Endothelin Receptor AntagonistsIBA 11/2014 - 02/2003
5	Neprilysin (Neutral Endopeptidase)IBA 06/2011 - 11/2004
4	Peptides (Polypeptides)IBA 07/2022 - 11/2004
4	oxidized low density lipoproteinIBA 06/2022 - 09/2003
4	Parathyroid Hormone (Parathormone)IBA 01/2022 - 01/2017
4	Fibroblast Growth Factor-23IBA 01/2021 - 05/2014
4	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021 - 04/2002
4	Messenger RNA (mRNA)IBA 12/2020 - 01/2011
4	Insulin (Novolin)FDA Link 11/2019 - 04/2010
4	Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA 01/2019 - 01/2012
4	Contrast MediaIBA 02/2017 - 09/2010
4	Soluble Guanylyl CyclaseIBA 01/2015 - 07/2006
4	Endothelin-Converting EnzymesIBA 06/2011 - 11/2004
4	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 04/2010 - 04/2002
3	Sodium-Glucose Transporter 2 InhibitorsIBA 09/2022 - 12/2017
3	empagliflozinIBA 09/2022 - 01/2019
3	Triglycerides (Triacylglycerol)IBA 01/2022 - 09/2003
3	Endothelin B ReceptorIBA 01/2022 - 04/2006
3	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 01/2022 - 03/2007
3	Brain Natriuretic Peptide (Natrecor)FDA Link 12/2021 - 06/2008
3	Hormones (Hormone)IBA 12/2020 - 01/2013
3	Phosphates (Orthophosphate)IBA 01/2018 - 07/2017
3	CalciumIBA 01/2018 - 02/2011
3	Blood Glucose (Blood Sugar)IBA 03/2016 - 01/2011
3	Interleukin-6 (Interleukin 6)IBA 09/2015 - 12/2005
3	Angiotensin IIIBA 01/2015 - 11/2007
3	salicylhydroxamic acid (SHAM)IBA 11/2013 - 04/2002
3	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2012 - 02/2009
3	riociguatIBA 01/2012 - 08/2010
3	NG-Nitroarginine Methyl Ester (L-NAME)IBA 01/2011 - 08/2008
3	AngiotensinogenIBA 11/2010 - 06/2007
3	Endothelin Receptors (Endothelin Receptor)IBA 08/2008 - 08/2002
2	CanagliflozinIBA 09/2022 - 01/2019
2	VaccinesIBA 07/2022 - 01/2014
2	MicroRNAs (MicroRNA)IBA 01/2022 - 12/2020
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 01/2019
2	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 11/2021
2	CollagenIBA 01/2022 - 10/2004
2	ProteomeIBA 01/2022 - 02/2021

Therapy/Procedure

13	Therapeutics 08/2018 - 09/2003
8	Renal Dialysis (Hemodialysis) 01/2022 - 09/2003
5	Surgical Instruments (Clip) 11/2013 - 04/2002
3	Cardiopulmonary Bypass (Heart-Lung Bypass) 06/2006 - 09/2003
3	Heart-Assist Devices 06/2006 - 09/2003